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UHN: Takeda licenses small molecule developed by researchers at UHN’s Krembil Brain Institute, targeting tau protein implicated in Alzheimer’s disease

(Toronto, April 11, 2023) – As announced today in a press release by biotechnology company Treventis, global pharmaceutical company Takeda...
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TREVENTIS™ utilizes a proprietary, patented discovery engine – Common Conformational Morphology (CCM) – to identify druggable active sites in misfolded protein targets.

CCM combines unique in silico models with deep expertise in model development (in vitro, ex vivo, in vivo) to enable rational drug design against misfolded protein targets.

Our Takeda-partnered lead program focuses on anti-misfolding small molecules in Alzheimer’s disease. We have further CCM-driven, U.S. DOD-funded efforts in oncology and other neurodegenerative diseases that show the wide utility of our technology platform.

Treventis has active
druggable CCM models for

Tau
Alpha Synuclein
p53
Amylin
And the Potential to Make 160+ Others…

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