Cancer

According to the World Health Organization, cancer is one of the world’s leading causes of death. Nearly 10 million people died of cancer in 2018. Cancer is a notorious killer and its primary mechanism is also notorious: rapid division and growth of abnormal cells that culminate in primary tumors and metastases that spread to other organs / parts of the body. What is perhaps less appreciated is that cancer is a protein misfolding disease. Several important oncogenes can mutate, resulting in proteins that cannot perform their original function and in fact, can result in toxic gains-of-function. TREVENTIS’ newest research direction combats these proteins.